A Proven Once-Daily Starting Dose of 5 mg1
DAYVIGO is a dual orexin receptor antagonist with convenient dosing, once nightly right before bed,
with at least 7 hours remaining before planned awakening.1
Recommended dosage1,2
- The recommended starting dose of DAYVIGO is 5 mg
- The dose may be increased to the maximum recommended dose of 10 mg, based on
clinical response and tolerability -
No need for dose adjustment based on age, sex, BMI, and renal impairment
- Exercise caution when using 10 mg in patients ≥65 years of age
- Patients with severe renal impairment may experience an increased risk of
somnolence
- For patients with moderate hepatic impairment, the maximum recommended dose is
5 mg once per night. DAYVIGO is not recommended for patients with severe hepatic
impairment- Patients with mild hepatic impairment may experience an increased risk of
somnolence
- Patients with mild hepatic impairment may experience an increased risk of
Administration
- DAYVIGO should be taken immediately before going to bed and with at least 7 hours
remaining before the planned time of awakening - DAYVIGO should not be taken more than once per night
- Time to sleep onset may be delayed if taken with, or soon after, a meal
- Avoid alcohol consumption with DAYVIGO
Dosage Adjustments
![Dosage Adjustments](/-/media/Project/EIsai/DayvigoHongkong/Getting-Started/dosage-table.jpg)
Dosage strengths1
- DAYVIGO tablets are available in 1 strength:
- 5 mg tablets: pale yellow, round, biconvex, film-coated tablets, and debossed with
"5" on one side and "LЄM" on the other side
- 5 mg tablets: pale yellow, round, biconvex, film-coated tablets, and debossed with
- The dose may be increased to the maximum recommended dose of 10mg
based on clinical response and tolerability
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